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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f56178910bfb88c90f08f7c413310b62defacdc0a420f37536e6c70742456e' 
  AND token = '0kioWQt+j5Ywb0E87LcXV2MPAMoFdQnvCLitJKwrArg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}