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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46de948f161be07df513b5a3ca19b2be6c4d81b12af9c7465d19b350e673694c' 
  AND token = '0iwZS2OTfU6Mdrpsl7Oe9b3hZKtDW/TqITEPpZ23cCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}