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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f3c41ca2e5414c337ccb55f788892ffae7b2a1a8e49de6baa36423409f50784' 
  AND token = '6Rd6sJ1fYZ9klONKU5aegSXp3wvVydEr+tI0tNx9Uo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}