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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4191b0b778c8e3113010b11edc3dd941b4bf7400580aa56b9f50c16ced9c3463' 
  AND token = 'LUrTz4QB34iHJPqu1zEcIfMXbP4o1Kf46MAEOhqlYr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}