SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b016f6e30c4d77002710fc19921a1b6ee2512293e8ff403467f8a4efde9ab882' 
  AND token = 'H2lSVCrA1wdmLn85tyAtrxuWyBiQq1IGKhBYEFttQNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}