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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5886636718de4936395dace0f80303f385b360395ad9c96c2a0fb7f05e68d520' 
  AND token = 'uLnjB7kWM+ERNDa6rMIQk+LJdKvv4sZMJLvM13nCq/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}