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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7543f8cdd5d235ac3d2295777bac0b52dd30a7c503d9a4c543e117b964bf2a99' 
  AND token = 'a6UH2NmFrxb77GTehN5QAJ+YWcFIniGcp4bF22XZVQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00080

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}