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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3de6a0f5a56f7de20db549ec078aaeed66273ad68357d28149d0e14729ce895' 
  AND token = 'hp9tG1agYg6mH1T/aTM0SCcrJZajIPjbwcWGVHHMBbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}