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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a457d058bd4cb3eef21839d5a70e5fffc920cbb8ca1d5acf7b4325f1c0bf260' 
  AND token = 'JBEFFyvg6f+Hwt4d4uea8fokAbvIUTkIMhaP+4Cz7z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}