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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4b6376f9f5619e98aa40d2cf7a6bb28daff679815ca1e393c242221c8f2a697' 
  AND token = 'K3Q0GQEHJJgwWR1TpNIIAUpasM8DOD5usnDvVK3FVxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}