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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4f2f1e68606298eaf134d37c28b28c0275a1f1ccb5642d31ead622727022c0' 
  AND token = 'JtgwtO7OgwDcRK5vqZ+t4rRbT3l89lyKWPAV+Z4rMJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}