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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ada45adf03ca39cfa353d01363cecb5cce55f0e7c46b64d464b7c6b4270457be' 
  AND token = 'J4mzzhaEQ5h/SzS4bFEYLXawjcE72uVLTsxRRzrIDQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}