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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6bfcc5b73d6e38633c84c7faecfb266e4c0e4a45a46337cee633d3106163a3c' 
  AND token = 'l9vFOTfehuxD6SqFN7H/4TkAZRGJjqnLAfgZGe/r0hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}