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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '619fc05c6a3afabd7bbee336f615dd95a3750087c61bcb911a532f21fa601f63' 
  AND token = '66pxkiMLzLzOrQ5zRly/PG3rYmy5NkOtfAyCFAZRyPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}