SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8251b844634e23e9650d0226a144c5b69a5d2a13af4ce11264305ac042f5f190' 
  AND token = 'dSr3cKyZv8ddvydDnxfrMVqSyLhbHdLGcewzP/Uky3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}