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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45da9fc42200caf5c1b7597abdfe27837ef2d60f5018b63f880be4e3e7e44f96' 
  AND token = 'ziR3rpyd/gEmcF8b6O5i3MkSJx3oT9WMpn6q8YGZnm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}