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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eee069bbee0728f99627053dbb442a6b388c49cd513d39adcde6da2217b051a' 
  AND token = '78Fo7oAIb7++2tFnj1snNPJq2xDPeceCd/Gcn7a7BrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}