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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ffe026045726b5261ffaaae941cca0b3711e5d1224001dd025bbcb335da0055' 
  AND token = 'owPnjabE5cAH8SZMeFVaiBnN5+2RrGJeP0UuhR87wSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}