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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07999664f1b53e737daf4f72710c0b3b228e3d4f1eb4fe95a33cb4e354465b38' 
  AND token = 'bsZpY3zBAqFQlrU/2UlxZxXl4ZH64Y0fsIlqgn/3OJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}