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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57705103b305df98a7d9feea8e10b00324dcf0716c8001a6e4b4016a9fcdc7cf' 
  AND token = 'P2Pm9FWT2wEZLd1OS5wp728yvBrsWGKcMH9GoJkAbGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}