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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb2f7b91b6e0ee428e4bf839f7cd7375c03b5bffcf0169d986c8b69bc6aad621' 
  AND token = 'CMi2/jwJI4QRIYYPsjsdJ2ekpFP2A5rRaUGe0tP70Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}