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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f0bd98d1986e51252b149ff9a6a821a994b79baa724712612614a2f3f4265d' 
  AND token = 'gXDrsS1Uj0GZgpoIkCELcfsSpZZfI8d6JdLIQyXl/5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}