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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b337af8a66a116a66c0d23dee23bf5603dc8a0ef0dae2f0ffc9f54c8fe5025b' 
  AND token = 'X+oisB//dkEIoxnOk3hBWxYLWvm0y5FlTPl50XtCjGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}