SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d234316bb6c441d82f7356895fb11016820e4402bc0cf76d5afbb664804bf05' 
  AND token = '4Xv92HSQIKfVpFTbBYm8OJuxaumrI3yJQ8BFTG6oyUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}