SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d728b2df5dcfd102ae81f5bb8b5a03198b28f560851d998f163e082f6cb6d5a' 
  AND token = '5/ZkiV8iUNXDwcrNmMLGmdDLsvgI2H8QzyXuOlp8Pto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}