SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0785675f2ea0d00d786cf96589c79cf69dcabbfeafb12540c3440cac1e2f85' 
  AND token = 'uRClptnjUvVVGI1dhIpF+kAOF7j+5soB+DkvsejlDIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}