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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f6b29b7f14b0e3a316171773d04ef1898e0087231b9155cb1082aaa8f7f0bd' 
  AND token = 'EbGuemq34L+8M+kYBhMOHUdJ0JAIRfwRFgXWRqRJ6z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}