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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71f686d219ea12a364c70a5f8fd4a122784c4534a6c3b7caa62eec929fe89649' 
  AND token = 'w6u4Z9Bhggt4Ylnny1Z6lxiomgULrb4d0Y6Fxr1g1No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}