SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eae9b96c1c494ec5171ddbc2cbe038dd75316789f4b091e6d632fb05228a5428' 
  AND token = 'rMSUEx0dri4DVK2WhdahuUoBe9wmYPbThS18w/VR3cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}