SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eef5a92d43cc171859fa2c05cd2955184dc4eba579415349b15809720651481' 
  AND token = 'DEIyHqhRwPjfBBSEQ/KxnciGCm6t4b3gs6QsD7Qh9I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}