SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1559f27d9a357512c7819898484b542d0d2bda97af1c35fd9621a572818c9a2' 
  AND token = 'pcRCbyJ0U8SWzVAqn1dH8jkPtZ1IRS97LhOQNb/efxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}