SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a9fcb8f0bc4868f5d6a03e4f8e04d147d9f90c179837bcf673bafa71a326ec9' 
  AND token = 'k6L1FLQSHw4YnTJ+lSmKzeDLujsxAz1aiYJECuc9Fmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}