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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755a3701ca1990c5b47fe5479b80b73b06f5f3bd703c076c87547325bd473395' 
  AND token = 'Ens6MWc8pIuCDSUJTGoFxK1J+4ZPu8geiogyCs8KI80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}