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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb0bf4c6d9fb50a8df79c47b408b8acd94129b0072364e0aa06f1036d66bdc7' 
  AND token = 'WJfPrmtIG++rpWkzRHZpsOXw15/h+2LPtdvXTEERmAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}