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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d31f1e25b97b72394132d01aca62946c44b19040b879bca52efd6b4d8729c2' 
  AND token = 'FasJUZr4Rw+uaso+kZf5rmDdkN9RyW27eN/ITmaAAj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}