SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f448eccf2f66c52e6f919bd6ac224ba517bae2604c5176f408ea4fcdc3d6aa8' 
  AND token = 'FwIjxTp8xQ+LGeUVs5AZKoEBM72aV+iGKBEhGia9NBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}