SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377e7b25cadf40a4e3b6863b8adc7825830535cf8bb9bf85cd03b642c6e953c2' 
  AND token = 'h3x7AplH2G9Xvjm5eiSBGjyrW9f03HMb508/LEVDwNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}