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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27fe42d001768ab608af5730c4fbf809a879f09989279fc971ec8694c2517a2d' 
  AND token = 'qhwtXSHcbGsRYwhShBYmyDrga9fHP7wqQ6Fp5q8qyRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}