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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d4d664414592e1dfd750f3f6f31581ef9acc97524cf376e49ba9f10e48c2cd6' 
  AND token = 'yrJHTPTE0yBSDF8lYxtKdUCr46i9/jItLODQOjgB86A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}