SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '132bcf2a4e60364049027a2dc189dd3184d8854d9e1bd91f561d2291a7043355' 
  AND token = 'qdf2HoApHJ4C7KzyvQZJIlqwX/S1ALUVytQcHYyjz1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}