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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bbc055599213f515568e05c1df4d3b7b23d1d8a11dfcae5502f2c4072579a02' 
  AND token = 'UdJBN+t5nhFxBPr4MLmat47cBWHo0v8TrdpZcufB5hU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}