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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a38c1072c3373eedc4cd141ab4d813ffc90fe516f6b9ab2e8886463fe8e153a' 
  AND token = 'knU3LO1eYM/iEvnHs3KNQN261RRAK575UFJCjfUYxOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}