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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb19ed5ab17cf37e46f3849f9fdb709ea127d0a04e11347d03929c0f94b98e41' 
  AND token = '/3Lp4MNjfp2mg0rsfGzIBJwqA4SPjDmL8x35LJc/RNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}