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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163e95e275a6b047791fb3c06315bdb6cdfc028791c51185e4cacf7dd5c413dc' 
  AND token = '75WmK3RjVUUJQilFTR3A3W2eQr9PzCWY7h5HgzlJpAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}