SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f05386f2896800ea9e4c844a6aabf59bf041e149c8eb166011e4f562170676' 
  AND token = 'LdFvRCEt4kd9qi4ENYo/+ONn5rOGB20uljE1xTl7wAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}