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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9be3deec18151b291bedd612d0402abefb808186cd39a85ac8c308d59b9fd231' 
  AND token = 'TvmCGMppDYLY44deoL7mI9G2Kt0PF/5VWsN/X0pCW/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}