SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26ee29a84428db1af68039b23c39972ba474c12aaf9598b5ac93514c6f7e7275' 
  AND token = 'cj3y3yAKPDlGqRPQU9wWwjwoL0634qVHXEAkfnkccCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}