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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163bfc0c95d1e6a0226f4126444027961317681e545d11fbf3827fa9473118b0' 
  AND token = 'PN/K2aUc0wmqaKN5nf6iiffFHQnR0XTqMNy6nDtMXQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}