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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be4e0c57daa5c4da4025aff3a32b446185b11357e37c4d708d1f53c63afa8c35' 
  AND token = 'PVSNE4WWSWRq4xv55MpkpaoiYwJs1aB07wPYZt+p48A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}