SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88bb403718b1aa3f823049d5103722ba05f4a36891d054025c1f76e5d2d27f3d' 
  AND token = 'Sm03nx7fkw3Pj5UJEPiocmU64RN5w8PmDUoZpAm43hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}